Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30498666 | 1.00 | GAA (0.57) | GAATRPV4KHKPGK1VCAM1 | |
| SCHEMBL31314338 | 0.91 | GAA (0.50) | GAATRPV4KHKPGK1VCAM1 | |
| SCHEMBL1291792 | 0.88 | GAA (0.46) | GAATRPV4KHKPGK1VCAM1 | |
| SCHEMBL6402873 | 0.88 | GAA (0.52) | GAATRPV4KHKVCAM1DYRK1A | |
| SCHEMBL145418 | 0.84 | TRPV4 (0.54) | TRPV4KHKPGK1VCAM1DYRK1A | |
| SCHEMBL404475 | 0.83 | GAA (0.46) | GAATRPV4KHKPGK1VCAM1 | |
| SCHEMBL23948546 | 0.80 | KHK (0.47) | GAATRPV4KHKCSNK1A1CLK4 | |
| SCHEMBL2476965 | 0.80 | KHK (0.52) | GAATRPV4KHKPGK1VCAM1 | |
| SCHEMBL20517749 | 0.80 | TRPV4 (0.39) | GAATRPV4KHKPGK1VCAM1 | |
| SCHEMBL601480 | 0.80 | TRPV4 (0.39) | GAATRPV4KHKPGK1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240023549-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2024-01-25 | — | — | US | disclosed |
| US-20240023549-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2024-01-25 | — | — | US | disclosed |
| EP-4247789-A1 | FUNGICIDAL ARYL AMIDINES | Corteva Agriscience LLC (US) | 2023-09-27 | — | — | EP | disclosed |
| CN-116529235-A | Fungicidal aryl amidines | 科迪华农业科技有限责任公司 | 2023-08-01 | — | — | CN | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| WO-2022109362-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022109362-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-05-27 | — | — | WO | disclosed |
| EP-3972414-A1 | FUNGICIDAL ARYL AMIDINES | Corteva Agriscience LLC (US) | 2022-03-30 | — | — | EP | disclosed |
| CN-113613494-A | Fungicidal arylamidines | 科迪华农业科技有限责任公司 | 2021-11-05 | — | — | CN | disclosed |
| US-4128545-A | DISPERSE, POLYESTER | BASF AKTIENGESELLSCHAFT (DE) | 1978-12-05 | — | — | US | disclosed |
| US-4113720-A | Disperse azo dye with diaminopyrimidine coupling component | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4083685-A | EXHAUSTION DYEING, AZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |
| US-4053465-A | CYANOPHENYL-AZO-AMINOPHENYL DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4042578-A | POLYESTERS | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
| US-4041025-A | FOR HYDROPHOBIC FIBERS SUCH AS POLYESTERS, YELLOW TO BLUE-GREEN SHADES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-3998802-A | POLYAMIDES, CELLULOSE ESTERS, POLYESTERS, POLYACRYLONITRILES | BASF AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
| US-3993619-A | AZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3956264-A | Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CYP1A1, CYP1A2, CYP1B1 | GAA 512/4885TRPV4 4224/4885KHK 2631/4885 |
| US-20240023549-A1 | FUNGICIDAL ARYL AMIDINES | CYP1A1, CYP1A2, CYP1B1 | GAA 512/4885TRPV4 4224/4885KHK 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.