Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 13/20 | 0.75 |
| ▸ | PYGM | P11217 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30249725 | 0.95 | PYGL (0.73) | PYGLPYGMMAPTSETD7MEN1 | |
| SCHEMBL7074047 | 0.88 | PYGL (0.66) | PYGLPYGMMAPTSETD7MEN1 | |
| SCHEMBL6431786 | 0.86 | PYGL (1.00) | PYGLPYGMMAPT | |
| SCHEMBL30249770 | 0.85 | PYGL (0.73) | PYGLPYGMMAPTMEN1KMT2A | |
| SCHEMBL7126045 | 0.85 | PYGL (0.73) | PYGLPYGMMAPTMEN1KMT2A | |
| SCHEMBL6431819 | 0.80 | PYGL (1.00) | PYGLPYGMMAPT | |
| SCHEMBL6432282 | 0.80 | PYGL (0.84) | PYGLPYGMMAPTSETD7MEN1 | |
| SCHEMBL4308346 | 0.80 | PYGL (1.00) | PYGLPYGMMAPTSETD7 | |
| SCHEMBL6432277 | 0.79 | PYGL (0.81) | PYGLPYGMMAPTSETD7MEN1 | |
| SCHEMBL7126675 | 0.77 | PYGL (0.71) | PYGLPYGMMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003510304-A | — | — | 2003-03-18 | — | — | JP | claimed |
| EP-1220832-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2002-07-10 | — | — | EP | claimed |
| WO-2001023347-A1 | NOVEL AROMATIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-04-05 | — | — | WO | claimed |