Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245159 | 0.93 | TSHR (0.58) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| SCHEMBL309590 | 0.93 | TSHR (0.58) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| Ammonia Solution, Strong SCHEMBL18921479 | 0.91 | TSHR (0.56) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| SCHEMBL10948447 | 0.91 | TSHR (0.61) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| SCHEMBL28747016 | 0.91 | TSHR (0.56) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| SCHEMBL7267486 | 0.88 | TSHR (0.57) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| Ether SCHEMBL21624615 | 0.86 | ALDH1A1 (0.46) | TSHRHPGDTDP1ALDH1A1CYP3A4 | |
| SCHEMBL28099112 | 0.85 | TSHR (0.50) | TSHRHPGDPLA2G2CNAAAHCAR2 | |
| SCHEMBL2023648 | 0.84 | TSHR (0.48) | TSHRHPGDPLA2G2CATMTDP1 | |
| SCHEMBL1557157 | 0.82 | TSHR (0.50) | TSHRHPGDPLA2G2CTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998901-B1 | Light-responding high color-rendering makeup cosmetic preparation | SHISEIDO CO LTD (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6306409-B1 | CHANGES ITS COLOR TO NATURAL OBSERVATION COLOR IN RESPONSE TO INTENSITY OF SURROUNDING LIGHT | SHISEIDO CO., LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-0998901-A1 | Light-responding high color-rendering makeup cosmetic preparation | SHISEIDO COMPANY LIMITED (JP) | 2000-05-10 | — | — | EP | disclosed |
| CN-1241133-A | Extracellular matrix production promoter | SHISEIDO CO LTD (JP) | 2000-01-12 | — | — | CN | disclosed |