Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27525143 | 0.96 | KMT2A (0.57) | KMT2AMEN1CNR1NPBWR1MCHR1 | |
| SCHEMBL7076843 | 0.87 | MEN1 (0.79) | KMT2AMEN1MAPTF10CYP3A4 | |
| SCHEMBL7077553 | 0.84 | F10 (0.65) | KMT2AMEN1CNR1MAPTF10 | |
| SCHEMBL6737341 | 0.83 | F10 (0.77) | F10 | |
| SCHEMBL7072134 | 0.82 | F10 (0.63) | KMT2AMEN1F10ALDH1A1L3MBTL1 | |
| Acetic Acid SCHEMBL27550442 | 0.82 | MEN1 (0.63) | KMT2AMEN1MAPTF10CYP3A4 | |
| SCHEMBL7074438 | 0.82 | F10 (0.69) | KMT2AMEN1MAPTF10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5733561 | 0.82 | F10 (0.75) | F10 | |
| SCHEMBL7071636 | 0.81 | F10 (0.53) | KMT2AMEN1NPBWR1MCHR1F10 | |
| SCHEMBL7074302 | 0.81 | F10 (0.53) | KMT2AMEN1NPBWR1MCHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |