Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27550418 | 0.96 | F10 (0.49) | F10TSHRKMT2ALMNAMMP2 | |
| SCHEMBL7071342 | 0.83 | CNR1 (0.57) | F10TSHRKMT2ALMNAMMP2 | |
| SCHEMBL7074838 | 0.82 | F10 (0.54) | F10TSHRKMT2ALMNAMMP2 | |
| SCHEMBL7074161 | 0.81 | KMT2A (0.58) | F10TSHRKMT2AALDH1A1MAPT | |
| SCHEMBL7072134 | 0.80 | F10 (0.63) | F10KMT2ALMNAALDH1A1GAA | |
| Acetic Acid SCHEMBL27538655 | 0.80 | CNR1 (0.53) | F10TSHRKMT2ALMNAMMP2 | |
| SCHEMBL7071636 | 0.79 | F10 (0.53) | F10KMT2ALMNAALDH1A1POLB | |
| Acetic Acid SCHEMBL27550443 | 0.79 | LMNA (0.52) | F10TSHRKMT2ALMNAMMP2 | |
| SCHEMBL7077553 | 0.79 | F10 (0.65) | F10KMT2ALMNAMAPTCA12 | |
| SCHEMBL7074220 | 0.79 | LMNA (0.71) | F10KMT2ALMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |