Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082462 | 0.90 | REN (0.45) | RENALDH1A1MAPT | |
| SCHEMBL6041360 | 0.89 | REN (0.49) | RENALDH1A1MAPT | |
| SCHEMBL7074419 | 0.89 | REN (0.46) | REN | |
| SCHEMBL7079425 | 0.85 | REN (0.54) | REN | |
| SCHEMBL7077032 | 0.82 | REN (0.51) | REN | |
| SCHEMBL7076800 | 0.82 | REN (0.49) | REN | |
| SCHEMBL7075943 | 0.82 | REN (0.49) | REN | |
| Bicarbonate SCHEMBL7550821 | 0.81 | REN (0.69) | REN | |
| SCHEMBL7083053 | 0.81 | REN (0.47) | REN | |
| SCHEMBL7082240 | 0.80 | REN (0.47) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |