SCHEMBL7074175

SCHEMBL7074175

[CH2]C(C)N(CCO)CCO

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758420 0.76 TSHR (0.43) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL7075510 0.75
SCHEMBL79660 0.75 MAPT (0.42) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL6326627 0.75 MAPT (0.42) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL28171320 0.74 MAPT (0.36) MAPTMEN1KMT2AALDH1A1
SCHEMBL2058214 0.73 MAPT (0.40) MAPTMEN1KMT2AALDH1A1TSHR
Water SCHEMBL3302021 0.73 MAPT (0.40) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL1977488 0.73 FDPS (0.39)
SCHEMBL12790540 0.73 MAPT (0.40) MAPTMEN1KMT2AALDH1A1TSHR
SCHEMBL17704232 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124903-B1 CATIONIC AZO-DYES BASF AG (DE) 2003-06-25 EP disclosed
US-6346609-B1 DISAZO DYES OR POLYAZO DYES BASF AKTIENGESELLSCHAFT (DE) 2002-02-12 US disclosed
EP-1124903-A1 CATIONIC AZO-DYES BASF AKTIENGESELLSCHAFT (DE) 2001-08-22 EP disclosed
EP-0949300-B1 Cationic azo dyestuffs containing sulfonic-acid groups BASF AG (DE) 2001-07-25 EP disclosed
EP-0955342-B1 Cationic azo dyes derived from aminobenzoic acid BASF AG (DE) 2001-07-11 EP disclosed
EP-1086180-A1 TRISAZO AND POLYAZO DYES AND THE MIXTURES THEREOF BASF AKTIENGESELLSCHAFT (DE) 2001-03-28 EP disclosed
WO-2000027929-A1 CATIONIC AZO-DYES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
US-6048969-A DISAZO DYE CATIONIC DYES BASF AKTIENGESELLSCHAFT (DE) 2000-04-11 US disclosed
US-6048968-A CATIONIC AZO DYES BASF AKTIENGESELLSCHAFT (DE) 2000-04-11 US disclosed
WO-1999064520-A1 TRISAZO AND POLYAZO DYES AND THE MIXTURES THEREOF BASF AKTIENGESELLSCHAFT (DE) 1999-12-16 WO disclosed
EP-0955342-A1 Cationic azo dyes derived from aminobenzoic acid BASF AKTIENGESELLSCHAFT (DE) 1999-11-10 EP disclosed
EP-0949300-A1 Cationic azo dyestuffs containing sulfonic-acid groups BASF AKTIENGESELLSCHAFT (DE) 1999-10-13 EP disclosed
US-5750661-A CATIONIC DYE FOR COLORING PAPER, SYNTHETIC POLYMER TEXTILES OR NATURAL FIBERS; CHEMICAL RESISTANCE, COLOR/WASHFASTNESS, SOLUBILITY BASF AKTIENGESELLSCHAFT (DE) 1998-05-12 US disclosed
EP-0594037-B1 Basic dyes based on amides of I-acid (1-hydroxy-6-aminonaphthalene-3-sulfonic acid) and amides of I-acid BASF AG (DE) 1997-09-24 EP disclosed
US-5571898-A Basic dyes based on amides of j-acid (1-hydroxy-6-aminonaphthalene-3-sulfonic acid) and amides of j-acid BASF AKTIENGESELLSCHAFT (DE) 1996-11-05 US disclosed
EP-0666287-A2 Basic dyes based on amides of the 1-hydroxy-6-aminonaphthalene-3-sulfonic acid and intermediates thereof BASF AKTIENGESELLSCHAFT (DE) 1995-08-09 EP disclosed
EP-0594037-A1 Basic dyes based on amides of I-acid (1-hydroxy-6-aminonaphthalene-3-sulfonic acid) and amides of I-acid BASF Aktiengesellschaft (DE) 1994-04-27 EP disclosed