Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074339 | 1.00 | NR1I2 (0.45) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL7076737 | 0.86 | MAPT (0.48) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL6095828 | 0.86 | MAPT (0.47) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL7076742 | 0.86 | MAPT (0.48) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL6791300 | 0.84 | ITGB1 (0.46) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL27360895 | 0.83 | MAPT (0.44) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL8313617 | 0.83 | MAPT (0.44) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL3929244 | 0.81 | MAPT (0.48) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL9982497 | 0.81 | MAPT (0.48) | NR1I2PGRPTGS2ITGB1ITGA4 | |
| SCHEMBL19236061 | 0.81 | MAPT (0.48) | NR1I2PGRPTGS2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859002-B1 | Process for producing chloroacetylaminothiazoleacetic acid derivatives | TOKUYAMA CORP (JP) | 2003-07-02 | — | — | EP | disclosed |
| CN-1071326-C | Process for producing chloroacetylaminothiazoleacetic acid derivatives | TOKUYAMA CORP (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1211571-A | Process for producing chloroacetylaminothiazoleacetic acid derivatives | TOKUYAMA CORP (JP) | 1999-03-24 | — | — | CN | disclosed |
| EP-0859002-A1 | Process for producing chloroacetylaminothiazoleacetic acid derivatives | TOKUYAMA CORPORATION (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5789598-A | SEPARATING CARBONATE BY-PRODUCT; NEUTRALIZATION | TOKUYAMA CORPORATION (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0781769-A1 | Process for production of alkoxycarbonylaminothiazole acetic acid derivative | TOKUYAMA CORPORATION (JP) | 1997-07-02 | — | — | EP | disclosed |