Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095828 | 0.92 | MAPT (0.47) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL7076737 | 0.89 | MAPT (0.48) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL7076742 | 0.89 | MAPT (0.48) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL7074339 | 0.84 | NR1I2 (0.45) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL7074341 | 0.84 | NR1I2 (0.45) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL8313617 | 0.83 | MAPT (0.44) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL27360895 | 0.83 | MAPT (0.44) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL9982497 | 0.81 | MAPT (0.48) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL19236061 | 0.81 | MAPT (0.48) | ITGB1ITGA4NR1I2PGRPTGS2 | |
| SCHEMBL10263157 | 0.81 | MAPT (0.49) | ITGB1ITGA4NR1I2PGRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087787-A1 | Novel thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-06 | — | — | US | disclosed |
| EP-1347970-A1 | NOVEL THIOESTER DERIVATIVES OF THIAZOLYL ACETIC ACID AND THEIR USE IN THE PREPARATION OF CEPHALOSPORIN COMPOUNDS | Orchid Chemicals and Pharmaceuticals Limited (IN) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002053563-A1 | NOVEL THIOESTER DERIVATIVES OF THIAZOLYL ACETIC ACID AND THEIR USE IN THE PREPARATION OF CEPHALOSPORIN COMPOUNDS | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2002-07-11 | — | — | WO | disclosed |
| US-6388070-B1 | CHEMICAL INTERMEDIATE | ORCHID CHEMICALS & PHARMACEUTICALS LTD. (IN) | 2002-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087787-A1 | Novel thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds | ACOT7, ACACA, COASY | ITGB1 4824/4885ITGA4 4825/4885NR1I2 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.