SCHEMBL7074712

SCHEMBL7074712

CN(C)CCc1cccc(C(=O)O)c1N

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.51
CASP7 P55210 1/20 0.51
CASP6 P55212 1/20 0.51
HTR2A P28223 4/20 0.47
HMGB1 P09429 1/20 0.45
FOLH1 Q04609 2/20 0.45
TAAR1 Q96RJ0 4/20 0.42
HTR6 P50406 4/20 0.42
HTR1A P08908 3/20 0.40
HTR1B P28222 3/20 0.40
HTR7 P34969 3/20 0.40
HTR2C P28335 3/20 0.40
HTR2B P41595 3/20 0.40
HTR1D P28221 2/20 0.40
DRD3 P35462 2/20 0.40
HTR5A P47898 2/20 0.40
DRD1 P21728 1/20 0.40
HTR1E P28566 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA2B P29275 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7770609 0.86 G6PD (0.44) G6PDCASP7CASP6HMGB1FOLH1
SCHEMBL10425883 0.85 G6PD (0.41) G6PDCASP7CASP6HTR2AFOLH1
SCHEMBL110298 0.83 FOLH1 (0.65) HTR2AFOLH1TAAR1HTR6HTR1A
SCHEMBL5135887 0.81 G6PD (0.56) G6PDCASP7CASP6HMGB1FOLH1
SCHEMBL808482 0.79 G6PD (0.57) G6PDCASP7CASP6HMGB1FOLH1
SCHEMBL30762619 0.79 G6PD (0.57) G6PDCASP7CASP6HMGB1FOLH1
SCHEMBL7157314 0.79 G6PD (0.53) G6PDCASP7CASP6HMGB1MMP2
SCHEMBL7720169 0.78 G6PD (0.56) G6PDCASP7CASP6HMGB1FOLH1
SCHEMBL6832900 0.78 G6PD (0.56) G6PDCASP7CASP6HMGB1FOLH1
SCHEMBL3447161 0.78 BID (0.46) G6PDCASP7CASP6HMGB1DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124903-B1 CATIONIC AZO-DYES BASF AG (DE) 2003-06-25 EP disclosed
EP-1124903-A1 CATIONIC AZO-DYES BASF AKTIENGESELLSCHAFT (DE) 2001-08-22 EP disclosed
EP-0955342-B1 Cationic azo dyes derived from aminobenzoic acid BASF AG (DE) 2001-07-11 EP disclosed
WO-2000027929-A1 CATIONIC AZO-DYES BASF AKTIENGESELLSCHAFT (DE) 2000-05-18 WO disclosed
EP-0955342-A1 Cationic azo dyes derived from aminobenzoic acid BASF AKTIENGESELLSCHAFT (DE) 1999-11-10 EP disclosed