SCHEMBL7074832

SCHEMBL7074832

CCS(=O)(=O)NC(C(=O)NCCc1cc(OC)c(OCC#CC2CC2)c(OC)c1)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KMT2A Q03164 9/20 0.35
MEN1 O00255 7/20 0.35
RAB9A P51151 1/20 0.35
GCGR P47871 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7030081 0.94 LMNA (0.38) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL7023002 0.92 LMNA (0.41) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL7026359 0.86 LMNA (0.38) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL6340627 0.84 KMT2A (0.44) LMNAKMT2AMEN1RAB9ATP53
SCHEMBL7103229 0.82 MEN1 (0.50) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL7028880 0.82 SMN1; SMN2 (0.39) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL7025725 0.82 KMT2A (0.41) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL7069790 0.82 LMNA (0.39) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL7028093 0.78 LMNA (0.37) LMNASMN1; SMN2KMT2AMEN1RAB9A
SCHEMBL7073956 0.77 KMT2A (0.38) LMNASMN1; SMN2KMT2AMEN1GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030229228-A1 Novel alpha-sulfin-and alpha-sulfonamino acid amides SYNGENTA CROP PROTECTION, INC. 2003-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030229228-A1 Novel alpha-sulfin-and alpha-sulfonamino acid amides ARSA, STS, CBR1 LMNA 4568/4885SMN1; SMN2 1574/4885KMT2A 2446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.