Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27568116 | 0.95 | F10 (0.52) | F10ALDH1A1LMNAMAPK1POLB | |
| SCHEMBL7074115 | 0.90 | KDM4E (0.59) | F10ALDH1A1LMNASMN1; SMN2KDM4E | |
| Acetic Acid SCHEMBL27550435 | 0.85 | ALDH1A1 (0.57) | F10ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL7069988 | 0.85 | F10 (0.59) | F10ALDH1A1LMNAMAPK1POLB | |
| SCHEMBL1303308 | 0.85 | F10 (0.71) | F10 | |
| SCHEMBL7074052 | 0.84 | F10 (0.56) | F10ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7074610 | 0.84 | GAA (0.59) | F10ALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6895022 | 0.84 | F10 (0.70) | F10 | |
| SCHEMBL6737341 | 0.83 | F10 (0.77) | F10 | |
| Hydrochloric Acid SCHEMBL5733561 | 0.83 | F10 (0.75) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1025086-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GmbH (DE) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999016751-A1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 1999-04-08 | — | — | WO | disclosed |