Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 14/20 | 0.40 |
| ▸ | ESR1 | P03372 | 13/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959283 | 0.71 | ESR2 (0.51) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL6806691 | 0.70 | ESR2 (0.46) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL6794474 | 0.69 | ESR2 (0.45) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL10728137 | 0.68 | ESR2 (0.50) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL7070362 | 0.66 | MAOB (0.45) | ESR2ESR1MAOAMAOBCYP26A1 | |
| SCHEMBL11738329 | 0.66 | ESR2 (0.42) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL6800723 | 0.66 | ESR2 (0.46) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL16013800 | 0.64 | MAOA (0.38) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL7070791 | 0.63 | ESR2 (0.38) | ESR2ESR1MAOAMAOBPRKCI | |
| SCHEMBL6806169 | 0.62 | MAOA (0.46) | ESR2ESR1MAOAMAOBPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339662-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046134-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2002-06-13 | — | — | WO | disclosed |