Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28387593 | 0.88 | ALDH1A1 (0.54) | MAOBCYP3A4LMNAALDH1A1KDM4E | |
| SCHEMBL7076952 | 0.82 | MAOB (0.55) | MAOBCYP3A4ALDH1A1KDM4ENPC1 | |
| SCHEMBL7133925 | 0.81 | ALDH1A1 (0.57) | MAOBLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2120395 | 0.80 | ATM (0.44) | MAOBCYP3A4POLBKDM4ENPC1 | |
| SCHEMBL7154660 | 0.75 | MAOB (0.47) | MAOBLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL4348338 | 0.74 | KDM4E (0.60) | MAOBLMNAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27282516 | 0.74 | SMN1; SMN2 (0.48) | MAOBNPSR1SMN1; SMN2 | |
| N-Benzylmethylamine SCHEMBL11522198 | 0.73 | MAOB (0.71) | MAOBALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL27609740 | 0.73 | MAPT (0.57) | MAOBCYP3A4ALDH1A1KDM4ERAB9A | |
| SCHEMBL7118017 | 0.72 | PPIB (0.43) | MAOBLMNAALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322632-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | Biogal Pharmaceutical Co., Ltd (HU) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024677-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002024676-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | TEVA PHARMACEUTICALS INDUSTRIES, LTD. (IL) | 2002-03-28 | — | — | WO | disclosed |