Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 8/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 3/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7073981 | 0.98 | ITGB3 (0.46) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7071446 | 0.96 | ITGB3 (0.52) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7075074 | 0.95 | ITGB3 (0.50) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7071421 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7073087 | 0.93 | ITGB3 (0.52) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7079100 | 0.92 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Hydrochloric Acid SCHEMBL7078468 | 0.92 | ITGB3 (0.51) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7076225 | 0.91 | ITGB3 (0.58) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7075689 | 0.90 | KDM4E (0.42) | ITGB3ITGA2BKDM4EPOLBPPARD | |
| Trifluoroacetic Acid SCHEMBL7075528 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BKDM4EPOLBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | WYETH (US) | 2003-06-12 | — | — | US | disclosed |
| US-6429214-B1 | INHIBITORS OF BONE RESORPTION | WYETH | 2002-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109523-A1 | Bicyclic antagonists selective for the alphavbeta3 integrin | ITGAV, ITGB2, ITGB3 | ITGB3 3/4885ITGA2B 7/4885KDM4E 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.