Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075835 | 1.00 | NPC1 (0.65) | NPC1MEN1KMT2AHDAC8NPSR1 | |
| SCHEMBL2525285 | 0.92 | NPC1 (0.77) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL2389717 | 0.92 | NPC1 (0.77) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL3807585 | 0.91 | NPC1 (0.71) | NPC1MEN1KMT2ANPSR1LMNA | |
| SCHEMBL15576719 | 0.88 | NPC1 (0.71) | NPC1MEN1KMT2AHDAC8NPSR1 | |
| SCHEMBL9610736 | 0.88 | NPC1 (0.71) | NPC1MEN1KMT2AHDAC8NPSR1 | |
| SCHEMBL9609515 | 0.88 | NPC1 (0.71) | NPC1MEN1KMT2AHDAC8NPSR1 | |
| SCHEMBL17765418 | 0.86 | NPC1 (0.74) | NPC1MEN1KMT2AHDAC8NPSR1 | |
| SCHEMBL1752680 | 0.86 | NPC1 (0.74) | NPC1MEN1KMT2AHDAC8NPSR1 | |
| SCHEMBL5837814 | 0.85 | NPC1 (0.55) | NPC1MEN1KMT2AHDAC8NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030120088-A1 | Optically active azetidincarboxamide-coordinated transition metal complexes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1319660-A1 | Optically active azetidincarboxamide-coordinated transition metal complexes as catalysts in asymmetric reduction | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030120088-A1 | Optically active azetidincarboxamide-coordinated transition metal complexes | AAAS, AP1M1, AP2A1 | NPC1 3078/4885MEN1 398/4885KMT2A 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.