AP2A1

AP-2 complex subunit alpha-1 · O95782 · AP2A1 on Sugi Atlas →

0 patent compounds predicted against AP2A1, 0 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours

Clinical trials — most relevant to AP2A1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
The Use of Inhaled Corticosteroids in the Treatment of Asthma is Children in the Emergency Room PHASE2/PHASE3COMPLETED
Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD PHASE3COMPLETED
Safety and Efficacy of AAV9/AP4B1 (BFB-101) For Patients With AP4B1-related Hereditary Spastic Paraplegia Type 47 (SPG47) PHASE1/PHASE2NOT_YET_RECRUITING
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt) PHASE1/PHASE2RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy PHASE2COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment PHASE2COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma PHASE1COMPLETED
Choline Effects - Pre-symptomatic AD PHASE1COMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport? nanUNKNOWN
Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients nanRECRUITING
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure nanUNKNOWN
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome nanCOMPLETED
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery nanCOMPLETED
Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study nanCOMPLETED
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus nanCOMPLETED
Studies on the Adaptive Responses to Hypoxia nanCOMPLETED
Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK) nanCOMPLETED
Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome nanRECRUITING
Investigation of Tumor Microenvironment After CRPC Along With Before and After Neoadjuvant Therapy for Prostate Cancer nanUNKNOWN
Biomarkers of CASH nanACTIVE_NOT_RECRUITING
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry Bad Cholesterol in the Blood nanCOMPLETED
High Altitude Medical Research Expedition Himlung 2013 - a Study of Human Adaption to Hypoxia nanCOMPLETED
Identification of Acute Intermittent Porphyria Modifying Genes nanRECRUITING
Genetic Polymorphism of the Androgen Receptor-Gene and Sexual Function in Middle Aged Women nanCOMPLETED
Mitochondrial Function of Immune Cells in Sepsis nanCOMPLETED
Genetics of Recurrent Early Onset Major Depression nanCOMPLETED
Transcriptomic Analysis to Put an End to Misdiagnosis in Patients With Rare Muscle Diseases nanRECRUITING
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a AP2A1 binder may also engage these)

ProteinNameSimilarity
P17426 1.000 P17426 →
AP2A2 AP-2 complex subunit alpha-2 0.990 landscape →
Q0VCK5 0.985 Q0VCK5 →
P17427 0.979 P17427 →
P18484 0.978 P18484 →
Q2KJ46 0.976 Q2KJ46 →
Q5ZIA5 0.976 Q5ZIA5 →
PSMD3 26S proteasome non-ATPase regulatory subunit 3 0.975 landscape →
D2SW95 0.974 D2SW95 →
COPB1 Coatomer subunit beta 0.973 landscape →
P23514 0.973 P23514 →
Q9JIF7 0.972 Q9JIF7 →
Q0JNK5 0.972 Q0JNK5 →
P14685 0.971 P14685 →
Q7QG73 0.971 Q7QG73 →
Q4R4I8 0.970 Q4R4I8 →
Q5R922 0.970 Q5R922 →
Q53PC7 0.970 Q53PC7 →
Q5R664 0.969 Q5R664 →
A0JN39 0.968 A0JN39 →
O35142 0.968 O35142 →
Q5R5F8 0.967 Q5R5F8 →
Q5R8N4 0.967 Q5R8N4 →
O55029 0.967 O55029 →
COPB2 Coatomer subunit beta' 0.967 landscape →
Q66HV4 0.966 Q66HV4 →
Q3SZA0 0.966 Q3SZA0 →
Q6P0H6 0.966 Q6P0H6 →
O88544 0.965 O88544 →
Q7Z3J2 0.965 Q7Z3J2 →