SCHEMBL7075952

SCHEMBL7075952

CC(=COc1c(Br)ccc(O)c1Br)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.33
TPMT P51580 1/20 0.32
AKR1C2 P52895 1/20 0.32
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
THRA P10827 2/20 0.31
THRB P10828 2/20 0.31
SLC22A12 Q96S37 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071848 0.73 CYP3A4 (0.37) AKR1C3TPMTTHRATHRB
SCHEMBL7076985 0.71 AKR1C3 (0.44) AKR1C3AKR1C2
SCHEMBL8130485 0.71 KDM4E (0.42) AKR1C3
Acetic Acid SCHEMBL27860234 0.69 KDM4E (0.38) AKR1C3TPMTAKR1C2ALOX15ALOX12
SCHEMBL27374622 0.68 AKR1C3 (0.44) AKR1C3ALOX15THRB
SCHEMBL7076716 0.68 KMT2A (0.44) AKR1C3
SCHEMBL2581335 0.67 AKR1C3 (0.38) AKR1C3
SCHEMBL219559 0.67 AKR1C3 (0.38) AKR1C3
Methacrylic Acid SCHEMBL7077127 0.67 KDM4E (0.34) AKR1C3AKR1C2ALOX15ALOX12
SCHEMBL2812447 0.67 CA12 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030096172-A1 Hologram recording material composition and hologram recording medium DAISO CO., LTD. (JP) 2003-05-22 US disclosed