SCHEMBL2581335

SCHEMBL2581335

C/C(=C\Oc1ccc(O)cc1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LTA4H P09960 2/20 0.38
CPT1B Q92523 1/20 0.38
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
PARP10 Q53GL7 1/20 0.36
ELANE P08246 1/20 0.36
MAPT P10636 2/20 0.36
P4HB P07237 1/20 0.36
CALM1 P0DP23 1/20 0.36
RAB9A P51151 1/20 0.36
F3 P13726 1/20 0.36
XDH P47989 1/20 0.36
CA12 O43570 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219559 1.00 AKR1C3 (0.38) AKR1C3ESR1ESR2MEN1KMT2A
Bisphenol A SCHEMBL3371994 0.89 ESR1 (0.48) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL2808566 0.85 CA1 (0.48) MEN1KMT2AALDH1A1PARP10MAPT
SCHEMBL2811460 0.85 LMNA (0.48) AKR1C3MEN1KMT2AALDH1A1MAPT
SCHEMBL2811454 0.85 LMNA (0.48) AKR1C3MEN1KMT2AALDH1A1MAPT
SCHEMBL2808572 0.85 CA1 (0.48) MEN1KMT2AALDH1A1PARP10MAPT
SCHEMBL156818 0.84 AKR1C3 (0.50) AKR1C3MEN1KMT2AALDH1A1ELANE
SCHEMBL821031 0.84 AKR1C3 (0.50) AKR1C3MEN1KMT2AALDH1A1ELANE
SCHEMBL7098474 0.83 CYP19A1 (0.39) AKR1C3ALDH1A1PARP10MAPTRAB9A
SCHEMBL2811418 0.83 MEN1 (0.44) AKR1C3MEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110609445-B Polyoxometalate and heteropolyoxometalate compositions and methods of use thereof 默克专利有限公司 2023-10-03 CN disclosed
EP-2384457-B1 COATING COMPOSITIONS MERCK PATENT GMBH (DE) 2022-07-06 EP disclosed
EP-3812839-A1 POLYOXOMETALATE AND HETEROPOLYOXOMETALATE COMPOSITIONS AND METHODS FOR THEIR USE Merck Patent GmbH (DE) 2021-04-28 EP disclosed
CN-110609445-A Polyoxometallate and heteropolyoxometalate compositions and methods of use thereof AZ电子材料卢森堡有限公司 2019-12-24 CN disclosed
EP-3276416-A1 METHOD FOR GENERATING NANORODS ARRAYS USING POLYOXOMETALATE AND HETEROPOLYOXOMETALATE COMPOSITIONS AZ Electronic Materials Luxembourg S.à.r.l. (LU) 2018-01-31 EP disclosed
EP-3095008-A1 POLYOXOMETALATE AND HETEROPOLYOXOMETALATE COMPOSITIONS AND METHODS FOR THEIR USE AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2016-11-23 EP disclosed
US-9418836-B2 Polyoxometalate and heteropolyoxometalate compositions and methods for their use AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-08-16 US disclosed
US-9409793-B2 Spin coatable metallic hard mask compositions and processes thereof AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-08-09 US disclosed
US-9146467-B2 Coating compositions MERCK PATENT GMBH (DE) 2015-09-29 US disclosed
US-20150200090-A1 SPIN COATABLE METALLIC HARD MASK COMPOSITIONS AND PROCESSES THEREOF AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2015-07-16 US disclosed
US-20150200091-A1 POLYOXOMETALATE AND HETEROPOLYOXOMETALATE COMPOSITIONS AND METHODS FOR THEIR USE AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. 2015-07-16 US disclosed
US-20130236833-A1 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-09-12 US disclosed
US-8455176-B2 Coating composition AZ ELECTRONIC MATERIALS USA CORP. (US) 2013-06-04 US disclosed
EP-2384457-A2 COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2011-11-09 EP disclosed
WO-2010055406-A2 COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
US-20100119972-A1 COATING COMPOSITION MERCK PATENT GMBH (DE) 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100119972-A1 COATING COMPOSITION S100A9, CAPG, C5 AKR1C3 4128/4885ESR1 2137/4885ESR2 1875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.