Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 10/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999861 | 0.95 | PTGS2 (0.45) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL7080519 | 0.80 | NPC1 (0.46) | LMNAMAPTSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL1001487 | 0.80 | PTGS2 (0.44) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL8579553 | 0.79 | PTGS1 (0.59) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL360725 | 0.79 | PTGS1 (0.59) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL8960142 | 0.79 | PTGS2 (0.54) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL5846200 | 0.79 | PTGS2 (0.54) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| Hydrochloric Acid SCHEMBL1177638 | 0.78 | PTGS1 (0.57) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL2818028 | 0.77 | PTGS2 (0.61) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL2852282 | 0.77 | PTGS2 (0.61) | PTGS2PTGS1CXCR1CXCR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013636-B1 | Preparation of allylic aromatic compounds | AMERSHAM HEALTH AS (NO) | 2003-07-09 | — | — | EP | disclosed |
| US-6284894-B1 | AROMATIC AMINE IS REACTED FIRST WITH A NITRITE AND THEN WITH AN ALLYLIC OLEFIN HAVING AN ELIMINATABLE TERMINAL SUBSTITUENT. | NYCOMED IMAGING AS (NO) | 2001-09-04 | — | — | US | disclosed |
| EP-1013636-A1 | Preparation of allylic aromatic compounds | NYCOMED IMAGING AS (NO) | 2000-06-28 | — | — | EP | disclosed |