Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 10/20 | 0.47 |
| ▸ | OXTR | P30559 | 9/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.47 |
| ▸ | BRD4 | O60885 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590690 | 0.93 | OXTR (0.51) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL4590243 | 0.92 | OXTR (0.49) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL4590281 | 0.87 | AVPR1B (0.56) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL4590704 | 0.87 | AVPR1B (0.58) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL4590188 | 0.86 | OXTR (0.49) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL2495591 | 0.85 | OXTR (0.50) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL2494928 | 0.84 | AVPR1B (0.56) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL4589816 | 0.84 | AVPR1B (0.56) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL2499968 | 0.84 | BRD4 (0.49) | AVPR1BOXTRAVPR1ABRD4MEN1 | |
| SCHEMBL4590226 | 0.83 | OXTR (0.47) | AVPR1BOXTRAVPR1ABRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296976-A1 | NOVEL 1,3-DIHYDRO-2H-INDOL-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Sanofi-Aventis (FR) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001098295-A1 | NOVEL 1,3-DIHYDRO-2H-INDOL-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2001-12-27 | — | — | WO | disclosed |