Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.76 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.55 |
| ▸ | CCR9 | P51686 | 2/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378162 | 0.87 | CCR2 (1.00) | CCR2PLA2G10GPR35NOD2NOD1 | |
| SCHEMBL29845455 | 0.86 | CCR2 (0.81) | CCR2PLA2G10GPR35NOD2NOD1 | |
| SCHEMBL3191922 | 0.86 | CCR2 (0.76) | CCR2GPR35CCR9 | |
| SCHEMBL6300900 | 0.85 | CCR2 (0.65) | CCR2GPR35F10ALDH1A1ECE1 | |
| SCHEMBL27811964 | 0.84 | CCR2 (0.76) | CCR2PLA2G10GPR35F10ALDH1A1 | |
| SCHEMBL3957310 | 0.84 | CCR2 (1.00) | CCR2PLA2G10GPR35CCR9F10 | |
| SCHEMBL3283216 | 0.83 | CCR2 (0.67) | CCR2PLA2G10NOD2NOD1CCR9 | |
| SCHEMBL3956671 | 0.83 | CCR2 (0.77) | CCR2PLA2G10GPR35CCR9F10 | |
| SCHEMBL3655296 | 0.83 | CCR9 (0.54) | CCR2GPR35CCR9MAPT | |
| SCHEMBL3664017 | 0.83 | CCR2 (0.55) | CCR2GPR35F10MAPTECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003504-B1 | INDOLE DERIVATIVES AND THEIR USE AS MCP-1 ANTAGONISTS | ASTRAZENECA AB (SE) | 2003-07-02 | — | — | EP | disclosed |