SCHEMBL7076594

SCHEMBL7076594

CC(=O)N1C(=O)NC(c2ccccc2)C1=O

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
ADORA3 P0DMS8 1/20 0.54
USP2 O75604 1/20 0.46
POLB P06746 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 1/20 0.43
ELANE P08246 1/20 0.43
ALDH1A1 P00352 2/20 0.43
EP300 Q09472 1/20 0.41
CREBBP Q92793 1/20 0.41
NOTUM Q6P988 1/20 0.40
TSHR P16473 1/20 0.40
TRPC5 Q9UL62 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6401309 0.83 LMNA (0.50) LMNAADORA3USP2MEN1KMT2A
SCHEMBL6399674 0.83 LMNA (0.50) LMNAADORA3USP2MEN1KMT2A
SCHEMBL77736 0.74 LMNA (0.61) LMNAADORA3MEN1KMT2ASMN1; SMN2
SCHEMBL7202789 0.71 LMNA (0.66) LMNAADORA3SMN1; SMN2TDP1ALDH1A1
SCHEMBL17622943 0.71 LMNA (0.66) LMNAADORA3SMN1; SMN2TDP1ALDH1A1
SCHEMBL845936 0.71 AR (0.61) LMNAADORA3POLBMEN1KMT2A
SCHEMBL6401313 0.71 LMNA (0.56) LMNAADORA3USP2MEN1KMT2A
SCHEMBL6105903 0.71 LMNA (0.56) LMNAADORA3USP2MEN1KMT2A
SCHEMBL6399678 0.71 LMNA (0.56) LMNAADORA3USP2MEN1KMT2A
SCHEMBL13684168 0.70 LMNA (0.56) LMNAADORA3USP2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1322744-A1 COATED, GRANULAR N-ALKYLAMMONIUM ACETONITRILE SALTS AND THEIR USE AS BLEACH ACTIVATORS BASF AKTIENGESELLSCHAFT (DE) 2003-07-02 EP claimed
WO-2002026927-A1 COATED, GRANULAR N-ALKYLAMMONIUM ACETONITRILE SALTS AND THEIR USE AS BLEACH ACTIVATORS BASF AKTIENGESELLSCHAFT (DE) 2002-04-04 WO claimed
EP-1322744-A1 COATED, GRANULAR N-ALKYLAMMONIUM ACETONITRILE SALTS AND THEIR USE AS BLEACH ACTIVATORS BASF AKTIENGESELLSCHAFT (DE) 2003-07-02 EP disclosed
EP-1313830-A1 USE OF PERCARBAMIC ACIDS AND DIACYL PERCARBAMATES AND PRECURSORS THEREFOR THE UNIVERSITY OF LEEDS (GB) 2003-05-28 EP disclosed
WO-2002026927-A1 COATED, GRANULAR N-ALKYLAMMONIUM ACETONITRILE SALTS AND THEIR USE AS BLEACH ACTIVATORS BASF AKTIENGESELLSCHAFT (DE) 2002-04-04 WO disclosed
WO-2002016538-A1 USE OF PERCARBAMIC ACIDS AND DIACYL PERCARBAMATES AND PRECURSORS THEREFOR THE UNIVERSITY OF LEEDS (GB) 2002-02-28 WO disclosed
EP-0303520-B1 Bleaching composition KAO CORP (JP) 1994-04-20 EP disclosed