SCHEMBL7076699

SCHEMBL7076699

CC(C)(C)c1c(C#N)c(C#N)c(C(C)(C)C)c(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26223296 0.80 KDM4E (0.32) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL24199124 0.73
SCHEMBL26223288 0.73 KDM4E (0.41) ALDH1A1HPGDKDM4EGLAMEN1
SCHEMBL21410208 0.73 KDM4E (0.31) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL21938187 0.73 KDM4E (0.31) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL21937265 0.73 KDM4E (0.31) ALDH1A1HPGDKDM4EGLAGAA
SCHEMBL23084787 0.73 MEN1 (0.55) ALDH1A1HPGDKDM4EGLAMEN1
SCHEMBL13062761 0.71
SCHEMBL12546315 0.71
SCHEMBL2946868 0.71 SQOR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030010621-A1 NOVEL SYNTHESIS OF PHTHALOCYANINES BY MICROWAVE IRRADIATION AGI CORPORATION (TW) 2003-01-16 US disclosed
US-6491796-B1 REACTING PHTHALOCYANINE, T-BUTYLPHTHALIC ANHYDRIDE, OR T-BUTYLPHTHALONITRILE WITH METAL CHLORIDE OR METAL ACETATE; CYCLIZATION, COMPLEXING AGI CORPORATION (TW) 2002-12-10 US disclosed