Sugi Predict

Sugi Predict / Compounds / SCHEMBL707684

SCHEMBL707684

SCHEMBL707684

O=C1c2ccccc2C(=O)c2cc(CCl)ccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 7/20 0.66
▸ RAB9A P51151 7/20 0.66
▸ SMN1; SMN2 Q16637 6/20 0.66
▸ MAPK1 P28482 5/20 0.66
▸ ALDH1A1 P00352 5/20 0.66
▸ LMNA P02545 5/20 0.66
▸ MAPT P10636 3/20 0.66
▸ L3MBTL1 Q9Y468 2/20 0.66
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ ELANE P08246 1/20 0.50
▸ CDC25B P30305 1/20 0.50
▸ TP53 P04637 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ TSHR P16473 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50
▸ S100A4 P26447 3/20 0.48
▸ BCL2 P10415 1/20 0.48
▸ MCL1 Q07820 1/20 0.48
▸ PLA2G1B P04054 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9209968 0.81 NPC1 (0.68) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL12807506 0.79 NPC1 (0.66) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL479017 0.79 NPC1 (0.66) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL29352712 0.79 NPC1 (1.00) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL36840 0.79 NPC1 (1.00) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL41511 0.79 NPC1 (0.66) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL9240147 0.79 NPC1 (0.66) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
Anthraquinone SCHEMBL6310187 0.79 NPC1 (1.00) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL9509522 0.79 NPC1 (0.66) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1
SCHEMBL30021053 0.79 NPC1 (0.66) NPC1RAB9ASMN1; SMN2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104292875-A Novel synthesis process of environment-friendly heavy metal vat golden orange G XIAO COUNTY KAIQI CHEMICAL TECHNOLOGY CO LTD 2015-01-21 — — CN claimed
WO-2003011917-A1 METHOD OF CURING ELASTOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-02-13 — — WO claimed
CN-109517204-B Super-smooth antibacterial material, preparation method thereof and super-smooth antibacterial catheter 威高集团有限公司 2021-04-30 — — CN disclosed
CN-109517204-A A kind of superslide anti-biotic material and preparation method thereof and superslide anti-microbial catheter 威高集团有限公司 2019-03-26 — — CN disclosed
CN-107744795-A A kind of hydrogenation-dechlorination catalyst converter 徐州工程学院 2018-03-02 — — CN disclosed
CN-105819225-B A kind of preparation method for manganese slag lightweight ceramic tile automatic charging device and its critical component 徐州工程学院 2017-12-26 — — CN disclosed
CN-106479213-A A kind of synthetic method of vat golden orange G original dyestuff 徐州开达精细化工有限公司 2017-03-08 — — CN disclosed
US-9278951-B2 Azolium and purinium salt anticancer and antimicrobial agents THE UNIVERSITY OF AKRON (US) 2016-03-08 — — US disclosed
US-9278951-B2 Azolium and purinium salt anticancer and antimicrobial agents THE UNIVERSITY OF AKRON (US) 2016-03-08 — — US disclosed
CN-104292875-A Novel synthesis process of environment-friendly heavy metal vat golden orange G XIAO COUNTY KAIQI CHEMICAL TECHNOLOGY CO LTD 2015-01-21 — — CN disclosed
US-20140142307-A1 AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS THE UNIVERSITY OF AKRON 2014-05-22 — — US disclosed
US-4677155-A Anthroquinonyl photosensitive polymers CIBA-GEIGY CORPORATION (US) 1987-06-30 — — US disclosed
EP-0112798-B1 LIGHT-SENSITIVE AND POSSIBLY CROSS-LINKABLE MIXTURE OF COMPOUNDS APT TO CONDENSATION AND ADDITION REACTIONS, REACTION PRODUCTS OBTAINED THEREBY AND USE THEREOF CIBA-GEIGY AG (CH) 1987-05-13 — — EP disclosed
US-4657842-A Photosensitive compositions of matter comprising epoxide compounds and functional anthraquinones CIBA-GEIGY CORPORATION (US) 1987-04-14 — — US disclosed
EP-0080975-B1 PHOTOSENSITIVE POLYMERS CIBA-GEIGY AG (CH) 1986-02-26 — — EP disclosed
EP-0165649-A2 Fluoropolyether compounds Montedison S.p.A. (IT) 1985-12-27 — — EP disclosed
EP-0112798-A1 Light-sensitive and possibly cross-linkable mixture of compounds apt to condensation and addition reactions, reaction products obtained thereby and use thereof CIBA-GEIGY AG (CH) 1984-07-04 — — EP disclosed
EP-0080975-A1 Photosensitive polymers CIBA-GEIGY AG (CH) 1983-06-08 — — EP disclosed
US-4001016-A POLYMERS WHICH CAN BE CROSS-LINKED BY PHOTOPOLYMERIZATION AGFA-GEVAERT, A.G. (DT) 1977-01-04 — — US disclosed
US-3936428-A Photopolymerizable polymer based on an etherified polyhydroxyalkyl acrylate BAYER AKTIENGESELLSCHAFT (DT) 1976-02-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140142307-A1 AZOLIUM AND PURINIUM SALT ANTICANCER AND ANTIMICROBIAL AGENTS PCNA, ITPA, MPI NPC1 2401/4885RAB9A 1559/4885SMN1; SMN2 3715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.