SCHEMBL41511

SCHEMBL41511

O=C1c2ccccc2C(=O)c2cc(CO)ccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.66
RAB9A P51151 7/20 0.66
ALDH1A1 P00352 6/20 0.66
SMN1; SMN2 Q16637 6/20 0.66
MAPK1 P28482 4/20 0.66
MAPT P10636 3/20 0.66
LMNA P02545 3/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
CHEK1 O14757 1/20 0.62
BCL2 P10415 1/20 0.54
MCL1 Q07820 1/20 0.54
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
CYP3A4 P08684 2/20 0.50
ELANE P08246 1/20 0.50
TTR P02766 1/20 0.50
CDC25B P30305 1/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30021053 1.00 NPC1 (0.66) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL6254969 0.98 NPC1 (0.63) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
Ammonia Solution, Strong SCHEMBL27784024 0.98 NPC1 (0.63) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
Bicarbonate SCHEMBL17747111 0.94 NPC1 (0.59) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL9423354 0.94 CHEK1 (0.65) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL3160291 0.94 ALDH1A1 (0.55) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL17208869 0.91 NPC1 (0.56) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
Acetaldehyde SCHEMBL5981408 0.91 NPC1 (0.61) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL47054 0.87 CHEK1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
Acetic Acid SCHEMBL6288239 0.85 ALDH1A1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119391158-A Laser color marking composition for black ground color, and preparation method and application thereof 四川大学 2025-02-07 CN claimed
CN-118121650-A Traditional Chinese medicine extract, preparation method thereof and blood component detection method 川北医学院 2024-06-04 CN claimed
CN-117683195-A Anthraquinone modified polyurethane and preparation method and application thereof 厦门理工学院 2024-03-12 CN claimed
EP-3943085-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2022-01-26 EP claimed
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH ZURICH (CH) 2021-06-24 US claimed
EP-3801507-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2021-04-14 EP claimed
WO-2020126442-A1 ONE-PART PHOTOCURABLE (METH) ACRYLATE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2020-06-25 WO claimed
CN-107846904-A New product 阿尔法生物农药有限公司 2018-03-27 CN claimed
CN-106928908-A A kind of new aeroge multifunctional material and preparation method thereof 广州市芯检康生物科技有限公司 2017-07-07 CN claimed
CN-105778404-A Flame retardant insulation foam material and preparation method thereof 苏州甫众塑胶有限公司 2016-07-20 CN claimed
WO-2000066091-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING POLYMERS BIOTECH AUSTRALIA PTY LIMITED (AU) 2000-11-09 WO claimed
WO-2000066090-A1 AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES BIOTECH AUSTRALIA PTY LIMITED (AU) 2000-11-09 WO claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0410287-B1 Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups CONSIGLIO NAZIONALE RICERCHE (IT) 1995-11-02 EP claimed
EP-0450461-B1 LHRH Analogs UNIV TULANE (US) 1995-09-06 EP claimed
US-5064442-A HAIR DYES L'OREAL (FR) 1991-11-12 US claimed
EP-0450480-A2 Somatostatin Analogues The Administrators of The Tulane Educational Fund (US) 1991-10-09 EP claimed
US-5041524-A Polyphosphazene derivatives containing carbonyl groups suitable for photoreticulation processes CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-08-20 US claimed
EP-0410287-A2 Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-01-30 EP claimed
EP-0369398-A2 Polyphosphazene derivatives containing carbonyl groups suitable for photoreticulation processes CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1990-05-23 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210186947-A1 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION TOMM70, TOMM34, TIMM50 NPC1 80/4885RAB9A 3373/4885ALDH1A1 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.