Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6394414 | 0.90 | NOTUM (0.32) | EGFRNOTUMNPSR1KDM4EMAPT | |
| SCHEMBL6305958 | 0.87 | TSHR (0.41) | EGFRNOTUMCHEK1KDM4EMAPT | |
| SCHEMBL6307314 | 0.87 | TSHR (0.41) | EGFRNOTUMCHEK1KDM4EMAPT | |
| SCHEMBL7136022 | 0.84 | EGFR (0.34) | EGFRKDM4EMAPTALDH1A1HTT | |
| SCHEMBL7074181 | 0.83 | GLA (0.37) | EGFRKDM4EMAPTALDH1A1HTT | |
| SCHEMBL6314583 | 0.83 | GLA (0.37) | EGFRKDM4EMAPTALDH1A1HTT | |
| SCHEMBL6306416 | 0.83 | GLA (0.37) | EGFRKDM4EMAPTALDH1A1HTT | |
| SCHEMBL6308373 | 0.82 | EGFR (0.36) | EGFRKDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL6309282 | 0.81 | TSHR (0.43) | CHEK1KDM4EMAPTALDH1A1HTT | |
| SCHEMBL6314533 | 0.80 | SMN1; SMN2 (0.42) | MAPTALDH1A1HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320536-A1 | $g(a)-SUBSTITUTED $g(b)-AMINOETHYL PHOSPHONATES | Ilex Oncology Research S.A. (CH) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002026752-A1 | α-SUBSTITUTED β-AMINOETHYL PHOSPHONATES | ILEX ONCOLOGY RESEARCH S.A. (CH) | 2002-04-04 | — | — | WO | disclosed |