SCHEMBL7076971

SCHEMBL7076971

COc1ccc(C)cc1.[LiH]

nearest known ligand 0.94

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.94
CA1 P00915 2/20 0.69
CA2 P00918 2/20 0.69
CA7 P43166 2/20 0.69
CA9 Q16790 2/20 0.69
CA12 O43570 1/20 0.69
CA14 Q9ULX7 1/20 0.69
RELA Q04206 1/20 0.68
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 4/20 0.52
MAPK1 P28482 2/20 0.52
MAPT P10636 3/20 0.50
GAA P10253 2/20 0.50
ALDH1A1 P00352 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 1/20 0.50
THRB P10828 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13925529 0.97
SCHEMBL12464 0.97
SCHEMBL19182839 0.97 ACHE (1.00) ACHECA1CA2CA7CA9
Methoxymethane SCHEMBL20136157 0.94 ACHE (0.94) ACHECA1CA2CA7CA9
SCHEMBL28860327 0.94 ACHE (0.94) ACHECA1CA2CA7CA9
SCHEMBL27287210 0.94
SCHEMBL29169384 0.94 ACHE (0.94) ACHECA1CA2CA7CA9
SCHEMBL27319762 0.94 ACHE (0.94) ACHECA1CA2CA7CA9
Ammonia Solution, Strong SCHEMBL21437378 0.94 ACHE (0.94) ACHECA1CA2CA7CA9
Hydrochloric Acid SCHEMBL28060919 0.94 ACHE (0.94) ACHECA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003066549-A2 SYNTHESIS OF SULFAMIDATES THE SCRIPPS RESEARCH INSTITUTE (US) 2003-08-14 WO disclosed