Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380119 | 0.92 | GRM5 (0.47) | NTRK1GRM5CYP19A1MAP4K4CYP1A2 | |
| SCHEMBL11373674 | 0.83 | NTRK1 (0.50) | NTRK1GRM5CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6578539 | 0.81 | GRM5 (0.52) | GRM5CYP19A1MAP4K4F10JAK2 | |
| SCHEMBL7077215 | 0.81 | GRM5 (0.40) | GRM5CYP19A1MAP4K4F10LMNA | |
| SCHEMBL11377412 | 0.80 | CYP19A1 (0.47) | NTRK1GRM5CYP19A1MAP4K4L3MBTL1 | |
| SCHEMBL7071680 | 0.80 | GRM5 (0.40) | GRM5CYP19A1MAP4K4L3MBTL1F10 | |
| SCHEMBL11379583 | 0.79 | BRAF (0.51) | NTRK1GRM5CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1122543 | 0.78 | CYP1A2 (0.59) | NTRK1GRM5CYP19A1MAP4K4CYP1A2 | |
| SCHEMBL7076280 | 0.78 | MAP4K4 (0.41) | GRM5CYP19A1MAP4K4L3MBTL1 | |
| SCHEMBL7072032 | 0.77 | MEN1 (0.54) | GRM5MAP4K4L3MBTL1F10PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181334-A1 | Herbicidal method | BAYER CROPSCIENCE LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
| WO-2003051119-A1 | NEW HERBICIDAL COMPOUNDS AND METHOD | BAYER CROPSCIENCE LIMITED (GB) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181334-A1 | Herbicidal method | DDT, HAAO, CYP4X1 | NTRK1 4528/4885GRM5 792/4885CYP19A1 302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.