SCHEMBL7077201

SCHEMBL7077201

C=C(C)C(=O)Oc1ccc(SCl)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.54
KMT2A Q03164 5/20 0.50
ATM Q13315 1/20 0.50
RAB9A P51151 1/20 0.38
LMNA P02545 2/20 0.37
MAPT P10636 4/20 0.37
MEN1 O00255 3/20 0.35
POLB P06746 2/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.34
PKM P14618 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
HSD17B10 Q99714 1/20 0.33
HSP90AA1 P07900 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19540354 0.85 ELANE (0.57) ELANEKMT2AATMRAB9ALMNA
SCHEMBL1232007 0.85 ELANE (0.57) ELANEKMT2AATMRAB9ALMNA
SCHEMBL14173266 0.85 ELANE (0.57) ELANEKMT2AATMRAB9ALMNA
SCHEMBL56436 0.84 ELANE (0.69) ELANEKMT2AATMRAB9ALMNA
SCHEMBL3135520 0.84 ELANE (0.56) ELANEKMT2AATMRAB9ALMNA
SCHEMBL7077981 0.81 ELANE (0.53) ELANEKMT2AATMRAB9ALMNA
SCHEMBL452065 0.79 ELANE (0.59) ELANEKMT2AATMLMNAMAPT
SCHEMBL4303407 0.79 ELANE (0.64) ELANEKMT2AATMRAB9ALMNA
SCHEMBL687176 0.79 ELANE (0.51) ELANEKMT2AATMLMNAMAPT
SCHEMBL16334971 0.79 ELANE (0.68) ELANEKMT2AATMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225230-A1 Polymers for antifouling coatings and a process for the preparation thereof JOTUN A/S 2003-12-04 US claimed
EP-0841380-B1 Method of making polymeric binders and use thereof in antifouling paints WITCO GMBH (DE) 1999-08-25 EP claimed
US-5891935-A Process for preparing polymeric binders and their use for antifouling paint systems WITCO GMBH (DE) 1999-04-06 US claimed
EP-0833870-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-04-08 EP claimed
WO-1996041842-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO claimed
US-20030225230-A1 Polymers for antifouling coatings and a process for the preparation thereof JOTUN A/S 2003-12-04 US disclosed
US-5891935-A Process for preparing polymeric binders and their use for antifouling paint systems WITCO GMBH (DE) 1999-04-06 US disclosed
EP-0833870-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF Jotun A/S (NO) 1998-04-08 EP disclosed
WO-1996041842-A1 POLYMERS FOR ANTIFOULING COATINGS AND A PROCESS FOR THE PREPARATION THEREOF JOTUN A/S (NO) 1996-12-27 WO disclosed