Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9937312 | 0.81 | HTT (0.39) | HTTALDH1A1PLA2G2CACACB | |
| SCHEMBL143815 | 0.76 | ALDH1A1 (0.50) | ALDH1A1NPC1HSD17B10LMNAMEN1 | |
| SCHEMBL15443496 | 0.76 | HTT (0.58) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28152546 | 0.75 | HTT (0.52) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL805296 | 0.75 | HTT (0.62) | HTTALDH1A1FABP7HSD17B10MEN1 | |
| SCHEMBL28371570 | 0.75 | HTT (0.62) | HTTALDH1A1FABP7HSD17B10MEN1 | |
| SCHEMBL8308167 | 0.74 | HTT (0.56) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9937560 | 0.74 | HTT (0.56) | HTTALDH1A1FABP7HSD17B10MEN1 | |
| SCHEMBL11217411 | 0.74 | ALDH1A1 (0.48) | ALDH1A1NPC1HSD17B10LMNAMEN1 | |
| SCHEMBL18211788 | 0.73 | HTT (0.48) | HTTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057687-A1 | METHODS FOR PREPARING DOXORUBICIN DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-07-17 | — | — | WO | disclosed |