Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 11/20 | 0.44 |
| ▸ | CTSS | P25774 | 6/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4759889 | 0.82 | CA1 (0.50) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL1115800 | 0.82 | CTSK (0.50) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL12081321 | 0.82 | CTSK (0.50) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL13651409 | 0.82 | CTSK (0.50) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL28421522 | 0.82 | CA1 (0.50) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL2675134 | 0.82 | CA1 (0.59) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL13306565 | 0.82 | CA1 (0.50) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL20297781 | 0.80 | CA1 (0.53) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL20315234 | 0.80 | CA1 (0.53) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL3074858 | 0.80 | CA1 (0.53) | CA1CA2CA7CYP2D6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030180797-A1 | Identification of ligands for a receptor family and related methods | TRIAD THERAPEUTICS, INC. | 2003-09-25 | — | — | US | disclosed |