Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 15/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7082030 | 0.98 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL7085778 | 0.95 | HSD11B1 (0.54) | HSD11B1MEN1KMT2AGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL7083350 | 0.94 | HSD11B1 (0.53) | HSD11B1MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL6680933 | 0.90 | HSD11B1 (0.58) | HSD11B1MEN1KMT2AGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6680846 | 0.88 | HSD11B1 (0.57) | HSD11B1MEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL6897711 | 0.82 | HSD11B1 (0.62) | HSD11B1MEN1KMT2AGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6894594 | 0.81 | HSD11B1 (0.60) | HSD11B1MEN1KMT2AMAOAMAOB | |
| SCHEMBL6684564 | 0.79 | HSD11B1 (0.63) | HSD11B1MEN1KMT2A | |
| SCHEMBL7080304 | 0.78 | HSD11B1 (0.38) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7079043 | 0.78 | HSD11B1 (0.37) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | claimed |
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |