Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 12/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649679 | 0.75 | KDM4E (0.63) | ALDH1A1CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL839837 | 0.74 | ALDH1A1 (0.62) | RAD51ALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL30116740 | 0.72 | RAD51 (0.50) | RAD51LCKALKALDH1A1CYP1A2 | |
| SCHEMBL840433 | 0.72 | RAD51 (0.50) | RAD51LCKALKALDH1A1CYP1A2 | |
| SCHEMBL3328288 | 0.69 | LCK (0.45) | LCK | |
| SCHEMBL24489517 | 0.68 | ALDH1A1 (0.55) | ALDH1A1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL29587078 | 0.68 | MAPT (0.55) | ALKALDH1A1CYP1A2MAPTCYP2C9 | |
| SCHEMBL21622727 | 0.68 | ALDH1A1 (0.55) | RAD51ALKALDH1A1CYP1A2MAPT | |
| SCHEMBL29941239 | 0.67 | LCK (0.58) | LCK | |
| SCHEMBL7981080 | 0.67 | LCK (0.58) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121692-B1 | SUBSTITUTED HETEROCYCLES AS JANUS KINASE INHIBITORS | INCYTE CORP (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2003104391-A2 | ANTIBACTERIAL TARGETS IN ALLOIOCOCCUS OTITIDIS | WYETH HOLDINGS CORPORATION (US) | 2003-12-18 | — | — | WO | disclosed |