Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28149723 | 1.00 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRBTDP1ELANE | |
| SCHEMBL25279 | 0.95 | — | — | |
| SCHEMBL195450 | 0.95 | — | — | |
| SCHEMBL866067 | 0.95 | — | — | |
| SCHEMBL27753541 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL28072427 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL28212425 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL27405631 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| SCHEMBL27596446 | 0.93 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTDP1 | |
| Ethylene Glycol SCHEMBL9235064 | 0.87 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649691-B2 | Imidazolidone carbamate monomers made from vinyl ethylene carbonate reacted with N-aminoethylimidazolidone; emulsion polymerized with acrylate or vinyl acetate; coatings | AIR PRODUCTS POLYMERS, L.P. | 2003-11-18 | — | — | US | claimed |
| US-20030119982-A1 | Wet adhesion monomer and derived copolymers for latex paints | PINSCHMIDT ROBERT KRANTZ (US) | 2003-06-26 | — | — | US | claimed |
| US-6538143-B1 | Reaction product of vinyl ethylene carbonate, methacryloxypropylene carbonate, and allyloxypropylene carbonate; and alkyl or cyclic urea | AIR PRODUCTS POLYMERS, L.P. | 2003-03-25 | — | — | US | claimed |
| EP-1167356-A2 | Wet adhesion monomer and derived copolymers for latex paints | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-01-02 | — | — | EP | claimed |
| US-6649691-B2 | Imidazolidone carbamate monomers made from vinyl ethylene carbonate reacted with N-aminoethylimidazolidone; emulsion polymerized with acrylate or vinyl acetate; coatings | AIR PRODUCTS POLYMERS, L.P. | 2003-11-18 | — | — | US | disclosed |
| US-20030119982-A1 | Wet adhesion monomer and derived copolymers for latex paints | PINSCHMIDT ROBERT KRANTZ (US) | 2003-06-26 | — | — | US | disclosed |
| US-6538143-B1 | Reaction product of vinyl ethylene carbonate, methacryloxypropylene carbonate, and allyloxypropylene carbonate; and alkyl or cyclic urea | AIR PRODUCTS POLYMERS, L.P. | 2003-03-25 | — | — | US | disclosed |
| EP-1167356-A2 | Wet adhesion monomer and derived copolymers for latex paints | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119982-A1 | Wet adhesion monomer and derived copolymers for latex paints | VCL, CLTA, CLTB | ALDH1A1 649/4885TSHR 4769/4885THRB 3748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.