Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074060 | 0.91 | REN (0.48) | RENPDE4BSSTR5 | |
| SCHEMBL7079908 | 0.91 | REN (0.52) | RENPDE4BSSTR5 | |
| SCHEMBL7076766 | 0.91 | REN (0.54) | RENPDE4BSSTR5 | |
| SCHEMBL7084145 | 0.91 | REN (0.49) | RENPDE4BSSTR5 | |
| SCHEMBL7079511 | 0.91 | REN (0.54) | RENPDE4B | |
| SCHEMBL7082315 | 0.90 | REN (0.37) | RENPDE4B | |
| SCHEMBL7076678 | 0.89 | REN (0.49) | RENPDE4BSSTR5 | |
| SCHEMBL7084760 | 0.89 | REN (0.54) | RENPDE4BSSTR5ALDH1A1 | |
| SCHEMBL7080191 | 0.88 | REN (0.48) | RENPDE4BSSTR5 | |
| SCHEMBL7078446 | 0.87 | REN (0.51) | RENPDE4BSSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |