Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.48 |
| ▸ | KDM5A | P29375 | 2/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 2/20 | 0.45 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688462 | 0.87 | KDM4C (0.57) | KDM4CKDM5AKDM5BRBP4KDM4A | |
| SCHEMBL4737266 | 0.84 | RBP4 (0.48) | KDM4CKDM5AKDM5BCYP11B1RBP4 | |
| SCHEMBL15965171 | 0.83 | KLKB1 (0.47) | KDM4CKDM5AKDM5BCYP11B1RBP4 | |
| SCHEMBL24208400 | 0.82 | KDM4C (0.47) | KDM4CKDM5AKDM5BRBP4KDM4A | |
| SCHEMBL7265636 | 0.82 | CYP2E1 (0.57) | KDM4CKDM5AKDM5BCYP11B1RBP4 | |
| Trifluoroacetic Acid SCHEMBL4737904 | 0.79 | KDM4C (0.50) | KDM4CKDM5AKDM5BRBP4KDM4A | |
| SCHEMBL553449 | 0.79 | KLKB1 (0.55) | KDM4CKDM5AKDM5BRBP4KDM4A | |
| SCHEMBL21314995 | 0.78 | KDM4C (0.50) | KDM4CKDM5AKDM5BCYP11B1RBP4 | |
| SCHEMBL30504034 | 0.78 | KDM4C (0.50) | KDM4CKDM5AKDM5BCYP11B1RBP4 | |
| SCHEMBL26641207 | 0.77 | KDM4C (0.41) | KDM4CKDM5AKDM5BRBP4KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030229079-A1 | 1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof | PAYNE LINDA S (US) | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229079-A1 | 1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof | CYP2S1, IMPDH1, IDO1 | KDM4C 1486/4885KDM5A 2332/4885KDM5B 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.