⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL707861 | 1.00 | — | — | |
| SCHEMBL11765424 | 0.82 | — | — | |
| SCHEMBL11765418 | 0.82 | — | — | |
| SCHEMBL28460633 | 0.79 | — | — | |
| SCHEMBL7039612 | 0.72 | — | — | |
| SCHEMBL1059084 | 0.71 | — | — | |
| SCHEMBL1059082 | 0.71 | — | — | |
| SCHEMBL7814020 | 0.71 | — | — | |
| SCHEMBL6109225 | 0.70 | — | — | |
| SCHEMBL262486 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057992-A1 | BTK INHIBITORS FOR HEMATOPOIETIC MOBILIZATION | IZUMI RAQUEL (US) | 2015-04-23 | — | — | WO | claimed |
| WO-2015057992-A1 | BTK INHIBITORS FOR HEMATOPOIETIC MOBILIZATION | IZUMI RAQUEL (US) | 2015-04-23 | — | — | WO | disclosed |
| US-8124196-B2 | Fluorobicyclo[2.2.2]octane compound, method of producing the same, and applications thereof | FUJIFILM CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |
| US-20100231844-A1 | FLUOROBICYCLO[2.2.2]OCTANE COMPOUND, METHOD OF PRODUCING THE SAME, AND APPLICATIONS THEREOF | FUJIFILM CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2150533-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ETHENYLPHENYL ALCOHOLS | LONZA AG (CH) | 2010-07-14 | — | — | EP | disclosed |
| US-20100130745-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ETHENYLPHENYL ALCOHOLS | MCGARRITY JOHN | 2010-05-27 | — | — | US | disclosed |
| EP-2150533-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ETHENYLPHENYL ALCOHOLS | LONZA AG (CH) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008131932-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE ETHENYLPHENYL ALCOHOLS | LONZA AG (CH) | 2008-11-06 | — | — | WO | disclosed |
| EP-1988079-A1 | Process for the preparation of optically active ethenylphenyl-alcohols | LONZA AG (CH) | 2008-11-05 | — | — | EP | disclosed |