Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077831 | 0.81 | LCK (0.48) | TSHRLCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL8014583 | 0.80 | TSHR (0.41) | TSHRALDH1A1LCKPPARDZDHHC20 | |
| SCHEMBL26092121 | 0.78 | TSHR (0.44) | TSHRALDH1A1LCKPPARDZDHHC20 | |
| SCHEMBL7074742 | 0.75 | TSHR (0.38) | TSHR | |
| SCHEMBL585816 | 0.75 | TSHR (0.37) | TSHRALDH1A1FAAHADH1BADH1C | |
| SCHEMBL11766872 | 0.75 | LMNA (0.46) | TSHRALDH1A1FAAHADH1BADH1C | |
| SCHEMBL6455169 | 0.75 | LMNA (0.46) | TSHRALDH1A1FAAHADH1BADH1C | |
| SCHEMBL28975659 | 0.74 | TSHR (0.44) | TSHRALDH1A1LCKPPARDZDHHC20 | |
| SCHEMBL29018755 | 0.74 | TSHR (0.44) | TSHRALDH1A1LCKPPARDZDHHC20 | |
| SCHEMBL28975666 | 0.74 | TSHR (0.44) | TSHRALDH1A1LCKPPARDZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1354886-A1 | Process for the preparation of tertiary phosphines | Bayer Aktiengesellschaft (DE) | 2003-10-22 | — | — | EP | disclosed |