Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 4/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221703 | 0.82 | BRD9 (0.39) | BRD9ALDH1A1CYP2C9PTGER1GABRP | |
| SCHEMBL1436794 | 0.76 | HTT (0.40) | BRD9ALDH1A1HTTHSD17B10KDM4E | |
| SCHEMBL1435856 | 0.76 | SMN1; SMN2 (0.44) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL3049884 | 0.73 | GRM5 (0.38) | BRD9GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL17619511 | 0.73 | ALDH1A1 (0.56) | BRD9ALDH1A1ACACBACACAGABRP | |
| SCHEMBL1313637 | 0.73 | BRD9 (0.46) | BRD9ALDH1A1ACACBACACAGABRP | |
| SCHEMBL5708297 | 0.72 | LATS1 (0.41) | BRD9ALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL4889199 | 0.72 | SMN1; SMN2 (0.47) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1314087 | 0.71 | SMN1; SMN2 (0.47) | BRD9ALDH1A1ACACBACACAPOLB | |
| SCHEMBL1314007 | 0.71 | BRD9 (0.44) | BRD9ALDH1A1ACACBACACAGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130281-A1 | DPP IV inhibitors | HOFFMAN-LA ROCHE INC. | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130281-A1 | DPP IV inhibitors | DPP4, DPP3, DPP7 | BRD9 4597/4885ALDH1A1 133/4885ACACB 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.