SCHEMBL707873

SCHEMBL707873

Cc1c(F)cc([C@@H](C)N(C)C(=O)c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2C(O)C(=O)O)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.41
CNR2 P34972 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL701834 0.93 CNR1 (0.41) CNR1CNR2
SCHEMBL703178 0.86 CNR1 (0.51) CNR1
SCHEMBL707872 0.80 CNR1 (0.51) CNR1CNR2
SCHEMBL700493 0.77 CNR1 (0.51) CNR1
SCHEMBL701833 0.73 CNR1 (0.51) CNR1CNR2
SCHEMBL704528 0.71 CNR1 (0.51) CNR1
SCHEMBL2064329 0.68 CNR1 (0.73) CNR1
SCHEMBL27782684 0.68 CNR1 (0.48) CNR1CNR2
SCHEMBL12918610 0.68 CNR2 (0.59) CNR1CNR2
SCHEMBL6123612 0.67 CNR1 (0.45) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121617-B1 CB1 RECEPTOR MODULATORS 7TM PHARMA AS (DK) 2014-01-22 EP disclosed
US-8124634-B2 CB1 receptor modulators 7TM PHARMA A/S (DK) 2012-02-28 US disclosed