Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468501 | 0.90 | BCHE (0.52) | ACHEBCHESLC6A4 | |
| SCHEMBL30130502 | 0.90 | BCHE (0.52) | ACHEBCHESLC6A4 | |
| SCHEMBL3407914 | 0.89 | ACHE (0.48) | ACHEBCHESLC6A4 | |
| SCHEMBL3408176 | 0.87 | SLC6A4 (0.56) | ACHESLC6A4 | |
| SCHEMBL30130509 | 0.87 | SLC6A4 (0.56) | ACHESLC6A4 | |
| SCHEMBL27603127 | 0.87 | HSD17B3 (0.44) | ACHEBCHESLC6A4 | |
| SCHEMBL3407874 | 0.85 | ACHE (0.49) | ACHEBCHESLC6A4 | |
| SCHEMBL5995940 | 0.84 | SLC6A4 (0.54) | ACHESLC6A4 | |
| SCHEMBL3404814 | 0.84 | SLC6A4 (0.52) | ACHESLC6A4 | |
| SCHEMBL30130448 | 0.84 | SLC6A4 (0.52) | ACHESLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301502-A1 | NOVEL COMPOUNDS AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | H. Lundbeck A/S (DK) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002008216-A1 | NOVEL COMPOUNDS AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | H. LUNDBECK A/S (DK) | 2002-01-31 | — | — | WO | disclosed |