SCHEMBL7079122

SCHEMBL7079122

OP(O)(S)=NCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 5/20 0.41
GRIN1 Q05586 4/20 0.41
FDPS P14324 1/20 0.41
NOS2 P35228 1/20 0.41
HPGD P15428 2/20 0.40
TRPA1 O75762 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
MIF P14174 1/20 0.40
TSHR P16473 2/20 0.39
IDO1 P14902 1/20 0.39
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
SIGMAR1 Q99720 2/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6686566 0.77 TSHR (0.52) ALDH1A1TSHRIDO1
SCHEMBL3073562 0.75 TSHR (0.42) FDPSHPGDTSHRCA12CA1
SCHEMBL6686557 0.71 IDO1 (0.38) GRIN2BGRIN1FDPSNOS2HPGD
SCHEMBL6682554 0.71 TSHR (0.55) ALDH1A1TSHRIDO1
SCHEMBL9348508 0.70 ALDH1A1 (0.41) GRIN2BGRIN1NOS2HPGDTRPA1
SCHEMBL3070712 0.70 TSHR (0.44) FDPSHPGDTSHRCA12CA1
SCHEMBL1653 0.68 ALDH1A1 (0.55) GRIN2BGRIN1NOS2HPGDTRPA1
SCHEMBL453564 0.67
SCHEMBL8371905 0.67 TSHR (0.57) FDPSHPGDTSHRCA12CA1
SCHEMBL6310521 0.67 HPGD (0.58) FDPSHPGDTSHRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed