SCHEMBL707927

SCHEMBL707927

CCCC[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
LTA4H P09960 2/20 0.35
PCSK9 Q8NBP7 1/20 0.35
PTGS2 P35354 1/20 0.34
NAAA Q02083 1/20 0.34
AR P10275 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HTT P42858 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CYP19A1 P11511 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975134 0.94 KCNH2 (0.39) TSHRLTA4HNAAAHTTSIGMAR1
SCHEMBL29199583 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL20483303 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL20483516 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL19470813 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL19470853 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL19470858 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL2101335 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL29199607 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1
SCHEMBL18107979 0.92 KCNH2 (0.42) NAAASMN1; SMN2HTTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10066059-B2 Sealing material composition for LED NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-09-04 US disclosed
US-9884928-B2 Polymers functionalized with activated nitrogen heterocycles containing a pendant functional group BRIDGESTONE CORPORATION (JP) 2018-02-06 US disclosed
CN-107075255-A LED encapsulant compositions 日产化学工业株式会社 2017-08-18 CN disclosed
US-20160289354-A1 POLYMERS FUNCTIONALIZED WITH ACTIVATED NITROGEN HETEROCYCLES CONTAINING A PENDANT FUNCTIONAL GROUP BRIDGESTONE CORPORATION (JP) 2016-10-06 US disclosed
EP-2128897-B1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE FUJITSU LTD (JP) 2015-05-06 EP disclosed
EP-2599836-B1 CURABLE COMPOSITION FOR SEMICONDUCTOR ENCAPSULATION ADEKA CORP (JP) 2015-03-25 EP disclosed
CN-102471581-B Curable composition for semiconductor encapsulation ADEKA CORP 2015-01-28 CN disclosed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
CN-102898655-B Method for preparing optically active polysilane UNIV HANGZHOU NORMAL 2014-06-25 CN disclosed
US-8716209-B2 Agent for post-etch treatment of silicon dielectric film, method of manufacturing semiconductor device, and semiconductor device FUJITSU LIMITED (JP) 2014-05-06 US disclosed
EP-2128897-A1 SILICON DIELECTRIC TREATING AGENT FOR USE AFTER ETCHING, PROCESS FOR PRODUCING SEMICONDUCTOR DEVICE, AND SEMICONDUCTOR DEVICE Fujitsu Limited (JP) 2009-12-02 EP disclosed
CN-100535054-C Silica film forming material, silica film and preparation method thereof FUJITSU LTD (JP) 2009-09-02 CN disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed
EP-1999167-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR Novolen Technology Holdings, C.V. (NL) 2008-12-10 EP disclosed
WO-2007106348-A2 ZIEGLER-NATTA CATALYST WITH IN SITU-GENERATED DONOR NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) 2007-09-20 WO disclosed
US-20070213204-A1 Ziegler-Natta catalyst with in situ-generated donor NOVOLEN TECHNOLOGY HOLDINGS C.V. 2007-09-13 US disclosed
EP-1769019-A1 METHOD OF MAKING BRANCHED POLYSILANES Dow Corning Corporation (US) 2007-04-04 EP disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
CN-1891757-A Silica film forming material, silica film and method of manufacturing the same FUJITSU LTD (JP) 2007-01-10 CN disclosed
WO-2005113648-A1 METHOD OF MAKING BRANCHED POLYSILANES DOW CORNING CORPORATION (US) 2005-12-01 WO disclosed