SCHEMBL7079407

SCHEMBL7079407

CC(C)N(C(=O)S)C(C)C.CCCN(CCC)C(=O)S

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
TSHR P16473 2/20 0.38
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TP53 P04637 1/20 0.34
CA1 P00915 3/20 0.33
P2RX1 P51575 2/20 0.31
P2RX4 Q99571 2/20 0.31
P2RX3 P56373 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
BCHE P06276 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535816 0.84 CA12 (0.52) CA12CA2CA9TSHRMAPK1
SCHEMBL578778 0.79 P2RX4 (0.31) TP53P2RX1P2RX4P2RX3BCHE
SCHEMBL6195760 0.75
SCHEMBL24024135 0.75 CA12 (0.36) CA12CA2CA9TSHRMAPK1
SCHEMBL10988112 0.72 CA12 (0.47) CA12CA2CA9TSHRMAPK1
SCHEMBL10901655 0.72 CA12 (0.41) CA12CA2CA9TSHRMAPK1
SCHEMBL25007406 0.71 CA12 (0.34) CA12CA2CA9TSHRMAPK1
SCHEMBL20740822 0.71 ALDH1A1 (0.44) CA12CA2CA9TSHRMAPK1
SCHEMBL3065351 0.70 CA12 (0.56) CA12CA2CA9TSHRALDH1A1
S-Ethyl Dipropylcarbamothioate SCHEMBL10793164 0.69 TSHR (0.80) CA12CA2CA9TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed