Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7191573 | 0.99 | HTR2C (0.39) | HTR2AHTR2CHTR2BCHRM2CHRM4 | |
| SCHEMBL7080304 | 0.82 | HSD11B1 (0.38) | HTR2AHTR2CHTR2BSIGMAR1P2RX7 | |
| SCHEMBL7079499 | 0.81 | HSD11B1 (0.39) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL7079630 | 0.81 | HSD11B1 (0.38) | HTR2AHTR2CHTR2BSIGMAR1P2RX7 | |
| Hydrochloric Acid SCHEMBL7135312 | 0.80 | HSD11B1 (0.38) | HSD11B1 | |
| SCHEMBL7079043 | 0.79 | HSD11B1 (0.37) | HTR2AHTR2CHTR2BP2RX7TAAR1 | |
| SCHEMBL7082807 | 0.78 | HSD11B1 (0.38) | HTR2AHTR2CHTR2BSIGMAR1P2RX7 | |
| SCHEMBL7082431 | 0.77 | HSD11B1 (0.38) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL7079481 | 0.77 | HSD11B1 (0.37) | HTR2AHTR2CHTR2BSIGMAR1P2RX7 | |
| Hydrochloric Acid SCHEMBL7082006 | 0.76 | HSD11B1 (0.38) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | claimed |
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |