Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137823 | 0.92 | TSHR (0.35) | DNM1LMNATSHR | |
| SCHEMBL27499887 | 0.89 | DNM1 (0.33) | DNM1LMNATSHR | |
| Dimethylamine SCHEMBL7084296 | 0.83 | — | — | |
| SCHEMBL16634457 | 0.83 | DNM1 (0.39) | DNM1LMNATSHR | |
| SCHEMBL17529712 | 0.81 | TSHR (0.44) | DNM1LMNATSHR | |
| SCHEMBL28410609 | 0.81 | TSHR (0.44) | DNM1LMNATSHR | |
| SCHEMBL15658250 | 0.81 | TSHR (0.44) | DNM1LMNATSHR | |
| SCHEMBL17529747 | 0.81 | TSHR (0.44) | DNM1LMNATSHR | |
| SCHEMBL1057106 | 0.76 | — | — | |
| SCHEMBL2860330 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090923-B1 | Process for the preparation of ruthenium hydrogenation catalysts and use thereof | DU PONT (US) | 2003-07-16 | — | — | EP | disclosed |
| EP-1090905-B1 | Use of ruthenium hydrogenation catalysts | DU PONT (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1031379-B1 | Catalyst comprising rutheniumcomplex, and use thereof in hydrogenation of unsaturated substrates, especially organic nitriles | DU PONT (US) | 2002-10-23 | — | — | EP | disclosed |
| EP-0839150-B1 | PROCESS FOR THE PREPARATION OF RUTHENIUM HYDROGENATION CATALYSTS AND PRODUCTS THEREOF | DU PONT (US) | 2001-12-05 | — | — | EP | disclosed |
| EP-0807119-B1 | PROCESS FOR THE PREPARATION OF RUTHENIUM COMPLEXES AND THEIR IN SITU USE AS HYDROGENATION CATALYSTS | DU PONT (US) | 2001-07-18 | — | — | EP | disclosed |
| EP-1090905-A1 | Process for the preparation of ruthenium hydrogenation catalysts and products thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1090923-A1 | Process for the preparation of ruthenium hydrogenation catalysts and products thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-1031379-A1 | Catalyst comprising rutheniumcomplex, and use thereof in hydrogenation of unsaturated substrates, especially organic nitriles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0807098-B1 | IMPROVED PROCESS FOR REDUCTIVE HYDROLYSIS OF NITRILES | DU PONT (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5763669-A | CONTACTING NITRILE WITH GASEOUS HYDROGEN IN PRESENCE OF ORGANORUTHENIUM CATALYST CONTAINING ORGANOPHOSPHORUS LIGAND, AGITATING THE NITRILE, HYDROGEN AND CATALYST TO FORM PRIMARY AMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-09 | — | — | US | disclosed |
| US-5741955-A | TRANSITION METAL COMPLEX CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5599962-A | FOR HYDROGENATING ORGANIC NITRILES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-02-04 | — | — | US | disclosed |
| US-5559262-A | PHOSPHINE LIGANDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |