Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489084 | 0.83 | MIF (0.71) | MIFGRIN2BTAAR1IDO1HTR2A | |
| SCHEMBL2340843 | 0.83 | MIF (1.00) | MIFGRIN2BTAAR1IDO1HTR2A | |
| SCHEMBL22642253 | 0.81 | MIF (0.47) | MIFGRIN2BTAAR1GRIN1ALDH1A1 | |
| SCHEMBL6660390 | 0.80 | MIF (0.67) | MIFGRIN2BTAAR1IDO1HTR2A | |
| SCHEMBL6662002 | 0.80 | MIF (0.77) | MIFGRIN2BTAAR1IDO1HTR2A | |
| SCHEMBL43367 | 0.77 | MIF (0.62) | MIFGRIN2BTAAR1IDO1HTR2A | |
| SCHEMBL19130316 | 0.77 | MIF (0.41) | MIFGRIN2BIDO1GRIN1ALDH1A1 | |
| SCHEMBL128465 | 0.74 | TAAR1 (0.60) | MIFGRIN2BTAAR1IDO1HTR2A | |
| SCHEMBL5103155 | 0.73 | TAAR1 (0.64) | MIFGRIN2BTAAR1IDO1HTR2A | |
| SCHEMBL3237564 | 0.73 | TAAR1 (0.64) | MIFTAAR1IDO1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320521-A1 | 2-THIOCARBAMOYLOXY AND 2-CARBAMOYLOXY DERIVATIVES OF CYCLOPENTYL-HEPTAN(EN)OIC ACID AS THERAPEUTIC AGENTS | Allergan, Inc. (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002026704-A1 | 2-THIOCARBAMOYLOXY AND 2-CARBAMOYLOXY DERIVATIVES OF CYCLOPENTYL-HEPTAN(ENE)OIC ACID AS THERAPEUTIC AGENTS | ALLERGAN INC. (US) | 2002-04-04 | — | — | WO | disclosed |