SCHEMBL7080137

SCHEMBL7080137

NC(=O)C(Cc1ccccc1)C(N)=S

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.55
MDM2 Q00987 1/20 0.53
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50
CYP1A2 P05177 1/20 0.48
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
SRR Q9GZT4 2/20 0.46
SLC1A3 P43003 2/20 0.46
SLC1A2 P43004 2/20 0.46
SLC1A1 P43005 2/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
SLC15A1 P46059 2/20 0.44
MMP8 P22894 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6896938 0.90 ALPI (0.57) EPHX1MDM2ALPIPKMPTGS1
SCHEMBL6827570 0.88 EPHX1 (0.50) EPHX1MDM2ALPIPKMPTGS1
SCHEMBL2109313 0.88 EPHX1 (0.68) EPHX1MDM2ALPIPKMPTGS1
SCHEMBL6562353 0.86 ALPI (0.61) EPHX1MDM2ALPIPKMPTGS1
SCHEMBL6896620 0.81 ALDH1A1 (0.50) MDM2ALDH1A1POLBL3MBTL1PPARG
SCHEMBL11558859 0.81 ALPI (0.55) EPHX1MDM2ALPIPKMPTGS1
SCHEMBL7349956 0.78 CYP1A2 (0.59) MDM2ALPIPKMPTGS1XIAP
SCHEMBL392827 0.77 CYP1A2 (0.70) MDM2ALPIPKMPTGS1XIAP
SCHEMBL6896818 0.77 PPARG (0.53) EPHX1MDM2ALDH1A1POLBL3MBTL1
SCHEMBL7345504 0.77 ALDH1A1 (0.50) EPHX1MDM2ALPIPKMPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed