Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.64 |
| ▸ | ACHE | P22303 | 3/20 | 0.54 |
| ▸ | TNKS | O95271 | 3/20 | 0.53 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 3/20 | 0.50 |
| ▸ | GABRD | O14764 | 3/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134490 | 0.89 | TNKS (0.57) | BCHEACHETNKSPARP1TNKS2 | |
| SCHEMBL7081024 | 0.80 | BCHE (0.58) | BCHEACHETNKSCYP3A4HPGD | |
| SCHEMBL360247 | 0.77 | CYP3A4 (0.82) | TNKSPARP1TNKS2PLA2G2APLA2G4A | |
| SCHEMBL30777197 | 0.77 | CYP3A4 (0.82) | TNKSPARP1TNKS2PLA2G2APLA2G4A | |
| SCHEMBL7206531 | 0.76 | CYP3A4 (0.55) | CYP3A4HPGDSMN1; SMN2KDM4EUSP2 | |
| SCHEMBL7083155 | 0.76 | CYP3A4 (0.55) | TNKSCYP3A4HPGDSMN1; SMN2KDM4E | |
| Flavone SCHEMBL22977569 | 0.73 | TNKS (0.81) | BCHEACHETNKSPARP1TNKS2 | |
| SCHEMBL10654593 | 0.73 | CYP3A4 (0.78) | TNKSPARP1TNKS2PLA2G2APLA2G4A | |
| SCHEMBL7080450 | 0.72 | BCHE (0.52) | BCHEACHEHPGDKDM4EALDH1A1 | |
| Flavone SCHEMBL110027 | 0.71 | TNKS (0.84) | BCHEACHETNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610738-B2 | Treatment of Alzheimer's Disease by combining both acetylcholinesterase inhibitory activity and antioxidant activity (by virtue of their carbamoyl and flavonoid pharmacophores) | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2003-08-26 | — | — | US | claimed |
| US-6610738-B2 | Treatment of Alzheimer's Disease by combining both acetylcholinesterase inhibitory activity and antioxidant activity (by virtue of their carbamoyl and flavonoid pharmacophores) | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2003-08-26 | — | — | US | disclosed |
| EP-1322632-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | Biogal Pharmaceutical Co., Ltd (HU) | 2003-07-02 | — | — | EP | disclosed |
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-09-12 | — | — | US | disclosed |
| WO-2002024677-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | CBR3, FOS, CBR1 | BCHE 375/4885ACHE 1755/4885TNKS 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.